Dec. 12, 2007 No poke, no pain. FDA-approved mouthpiece takes needles away from dental visits... Nov. 5, 2007 FDA approves gumEase® Cryo-Anesthetic dental mouthpiece for relief of dental pain without drugs... April 20, 2007 European CE Approval for gumEase® Cryoanesthetic Device... May 17, 2006 CryoDevices to Begin Manufacturing Advanced, State-Of-The-Art Dental Anesthetic Device ...